INSTI study

Primary resistance to integrase strand-transfer inhibitors in Europe

J Antimicrob Chemother doi:10.1093/jac/dkv202


M. Casadella` 1*, P. M. van Ham2, M. Noguera-Julian1,3, A. van Kessel2, C. Pou1, L. M. Hofstra2,4, J. R. Santos5, F. Garcia6, D. Struck4, I. Alexiev7, A. M. Bakken Kran8, A. I. Hoepelman2, L. G. Kostrikis9, S. Somogyi10, K. Liitsola11, M. Linka12, C. Nielsen13, D. Otelea14, D. Paraskevis15, M. Poljak16, E. Puchhammer-Sto¨ckl17, D. Stanekova´ 18, M. Stanojevic19, K. Van Laethem20, S. Zidovec Lepej21, B. Clotet1,3,4, C. A. B. Boucher22, R. Paredes1,3,4 and A. M. J. Wensing2 on behalf of the SPREAD programme†

1. IrsiCaixa AIDS Research Institute, Universitat Auto`noma de Barcelona, Badalona, Catalonia, Spain;
2. Department of Virology, Medical Microbiology, Utrecht Medical Centre, Utrecht, The Netherlands; \
3. Universitat de Vic-Universitat Central de Catalunya, Vic, Spain;
4. Laboratory of Retrovirology, Luxembourg Institute of Health, Luxembourg;
5. HIV Unit, Hospital Universitari Germans Trias I Pujol, Universitat Auto`noma de Barcelona, Badalona, Catalonia, Spain;
6. Complejo Hospitalario Univeristario de Granada, Instituto de Investigacio´n IBS, Granada, Cohorte de Adultos de la Red de Investigacio´n en SIDA (CoRIS) Spain;
7. National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria;
8. Institute of Clinical Medicine, Oslo, Norway;
9. University of Cyprus, Nicosia, Cyprus;
10. Robert Koch- Institute, Berlin, Germany;
11. National Institute of Health and Welfare, Helsinki, Finland;
12. National Reference Laboratory for HIV/AIDS, National Institute of Public Health, Prague, Czech Republic;
13. Statens Serum Institut, Copenhagen, Denmark;
14. National Institute for Infectious Diseases ‘Prof. Dr. Matei Bals’, Bucharest, Romania;
15. National Retrovirus Reference Center, University of Athens, Athens, Greece;
16.Slovenian HIV/AIDS Reference Centre, University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia;
17. University of Vienna, Vienna, Austria;
18. Slovak Medical University, Bratislava, Slovakia;
19. Faculty of Medicine, University of Belgrade, Belgrade, Serbia;
20. Clinical and Epidemiological Virology, Rega Institute for Medical Research, Department of Microbiology and Immunology, KU Leuven, Belgium; 21. University Hospital for Infectious Diseases ‘Dr. Fran Mihaljevic’, Zagreb, Croatia;
22. Department of Virology, Erasmus Medical Center, Rotterdam, The Netherlands